The best Side of cees dekker
The best Side of cees dekker
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2009, discovery of a new phenotype for bacteria in narrow nanofluidic slits; and very first detection of regional protein buildings together DNA using strong-state nanopores
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination perform.
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Because 2000, Dekker has shifted the leading focus of his perform toward biophysics where he reports the Attributes of one biomolecules and cells using the resources of nanotechnology. This modification of field was driven by his fascination for that extraordinary functioning of biological molecular structures, and also because of the long-phrase viewpoint that lots of attention-grabbing discoveries may be anticipated On this discipline.[five] Latest strains of investigate in his biophysics team are within the areas of:[6]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever study of your dynamics DNA supercoils and the discovery of supercoil hopping
Instance (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the motion of the DNA rod is shown.
We condition micro organism into varieties that deviate from their normal phenotype. Exclusively, I will show our capability to shape Are living E. coli micro organism into novel designs including rectangles, squares, triangles and circles.
He also found time to put in writing several textbooks, mail Virtually forty thousand tweets and guide a successful investigation team at Delft University of Know-how. ‘It doesn’t really feel like operate’, he says. ‘I’m just terribly curious.’
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Presently, we also recognized that it should be achievable to utilize just one semiconducting carbon nanotube to create a transistor — and we set out to really make it. We stretched particular person semiconducting nanotubes throughout metallic electrodes and employed the underlying silicon substrate as a gate electrode, creating The essential 3-terminal layout of the industry-influence transistor (Fig.
Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in gray, the rim in the pore is highlighted in red, and a 3D rendering from the movement with the DNA rod is shown.
2001, discovery of solitary-electron transistors at place temperature based upon nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery from the molecular structure of DNA restore enzymes with AFM
Developments in nanotechnology within the 1990s produced creating electronic gadgets from single molecules a chance. Cees Dekker recounts how his team produced a space-temperature transistor according to just one carbon nanotube.
2004, discovery of new physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; to start with electrochemistry with specific single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking ceesdekker.net of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical properties of double-stranded RNA; and initially single-molecule analyze of DNA translocation by a restriction-modification enzyme.