The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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Working with solitary-molecule optical and AFM imaging and force-spectroscopy techniques, we request to unravel the mechanistic areas of the framework and dynamics of chromosomes. Our analysis interests consist of:
1996, very first mesoscopic demand density waves devices; and 1st electrical measurements on only one steel nanocluster concerning nanoelectrodes
Again in 1991, Sumio Iijima with the NEC Company experienced described the synthesis of carbon nanotubes. Band composition calculations prompt that these nanotubes could show metallic band conduction. This is able to be a major benefit in excess of the conducting polymers we had explored, which have been, in reality, disordered semiconductors giving simply variable-selection hopping conductivity.
Non-equilibrium folding of personal DNA molecules recaptured approximately 1000 occasions in a very sound condition nanopore
2010, designed a completely new way (‘wedging transfer’) to govern nanostructures; initial report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores
From the yrs pursuing these discoveries, my investigation interests shifted to biophysics and nanobiology, and I turned a lot less involved with the event of nanotube electronics. The main focus of many scientists in the sector also shifted to graphene (in which, funnily sufficient, the first graphene ribbons ended up referred to as ‘nanotubes which can be Reduce open up along their duration’) immediately after the discovery of The 2-dimensional substance in 2004.
Duration control of personal carbon nanotubes by nanostructuring with the scanning tunneling microscope
Studying DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
‘You shouldn't just contemplate the thoughts of tomorrow, but also consider the questions from the day after tomorrow’
But carbon nanotubes have remained a investigate subject matter of substantial curiosity to several. In fact, the outlook on using carbon nanotubes to develop https://www.ceesdekker.net simple gadgets, in places for instance radio-frequency electronics, electronic electronics and flexible electronics, remains shiny.
Given that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from scientific tests of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. A lot more lately his investigate has centered on learning chromatin composition and cell division with micro organism on chip, while he is additionally attempting to finally Construct artificial cells from the bottom up.
1999, initially measurement of the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for your new Luttinger description of interacting electrons in nanotubes
2005, discovery on the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of long-range conformational changes in Mre11/DNA repair complexes; and first drive measurements over a DNA molecule within a nanopore
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and single-molecule experiments